Binswangers Disease

Information and facts about Eponymous diseases.

Binswanger's disease is a rare form of multi-infarct dementia caused by damage to deep white brain matter . It is characterized by loss of memory and intellectual function and by changes in mood.

Binswanger's disease is one of the neurological syndromes associated with hypertension . It is uncommon, but obviously devastating. The histologic findings are diffuse, irregular loss of axons and myelin accompanied by widespread gliosis . Small infarcts may be seen in the frontal lobes . The pathologic mechanism may be damage caused by severe atherosclerosis .

A patient with long term severe hypertension develops progressive dementia . CT scans of the head demonstrate a diffuse loss of deep hemispheric white matter.

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